Hoe 984

《英文msh詞典》Hoe 984
[入口詞] Hoe 984
[主題詞] Nomifensine
[藥動學] Dopamine Uptake Inhibitors
[英文釋義] An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases,renal failure also developed. (From Martindale,The Extra Pharmacopoeia,30th ed,p266)